TARGETING WEAKER OPPONENTS
In general, whether you are playing a cash game or tournament, you always want to try to exploit the weaker players at the table, and try to avoid the better players.
THE GAME IS ABOUT MAKING MONEY
Don’t get too caught up in pride, or trying to always beat the best. At the end of the day, this game is about making money. The best way to make money in poker is by targeting weaker players.
This is not to say to play every hand against weaker players, or to not play any hands with the better players.
But as a general rule of thumb it’s important to remember to exploit weak players, and avoid strong players.
Even the best players in the world constantly employ this strategy when at a table with mixed range of experience and skills.